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talquetamab will increase the level or impact of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Talquetamab leads to cytokine release syndrome (CRS) which will suppress action of CYP enzymes, leading to greater publicity of CYP substrates.Keep an eye on Intently (1)omaveloxolone will minimize the